Development of State of the Art Application Software Capable of Assessing Clinically Relevant Drug-Drug Interactions by Fujitsu Kyushu Systems Limited

May 31, 2011 · Filed Under PR, Trendy Products · Comments Off on Development of State of the Art Application Software Capable of Assessing Clinically Relevant Drug-Drug Interactions by Fujitsu Kyushu Systems Limited 


A drug-drug interaction or otherwise referred to as DDI is a pharmacological phenomenon whereby the presence of a second drug (inhibitor) alters the behavior and response of the body to a given dose of a first drug (substrate) leading to changes in the efficacy and safety of drugs when the two drugs are administered together, resulting in adverse side effects or even sometimes fatal death.

Generally, many drug candidates are identified by pharmaceutical companies based on highly specialized and target-specific assay systems which were then optimized and carefully screened through meaningful in vitro assays and animal studies; however still a number of these drug candidates fail in clinical trials (or even drop out of the market after they have been released) mostly due to safety reasons, one of them being potentially deadly DDI. Read more

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